Tuesday, 1 November 2011

Clinical Evaluation of Tentex Royal in Erectile Dysfunction

Clinical Evaluation of Tentex Royal in Erectile Dysfunction

A study was conducted to evaluate the clinical efficacy of Tentex Royal in patients with erectile viagra cialis online pharmacy pharmacy (ED). The study included 45 patients with a history of ED. Each patient was given Tentex Royal 2 capsules daily at night for 6 weeks. All patients had follow-up to evaluate the effect of the drug and to rule out any side effects after the second week and then every week for a further 4 weeks.

Among the 45 patients included in the study, 40 patients completed the treatment. Thirty two patients (80%) showed significant clinical improvement 16 patients (40%) were cured in 3 weeks and 12 patients (30%) showed improvement in 6 weeks. Thus, Tentex Royal is effective and safe in the treatment of patients with ED.

Introduction

Erectile dysfunction (ED) is a potentially devastating ailment that affects not only men, but also their sexual partners. The Massachusetts Male Aging Study revealed that age is the single most important variable associated with erectile difficulty. Currently, about 20-30 million American men are impotent, with projections of upto 47 million by the year 2020. This can be a rather difficult and embarrassing topic for most of these individuals to discuss. Moreover, most patients and healthcare professionals do not have an adequate understanding of the available treatment options. Hence, it has been estimated that only 5-10% of men with ED will seek medical intervention. Since this is one of the most under-treated conditions in the United States, the evaluation and management of impotence has become an emerging market, resulting in the expansion of numerous men’s impotence clinics.



Over the past few years, there has been an increased understanding of the physiology of erection and the pathophysiology of ED. We are beginning to understand the events leading to tumescence and detumescence at the cellular and molecular level. Combined with the advent of sophisticated diagnostic modalities, more and more of these patients are diagnosed with treatable organic causes of ED. Currently, there are a multitude of treatment options available, ranging from oral to injectable medications and various surgical treatments. A thorough understanding of penile physiology as well as current diagnostic and treatment modalities is necessary for proper evaluation and treatment of patients with ED.

Erectile dysfunction is a common problem in newly married couples. Impotence means that the penis is too limp to penetrate the vagina. More than 90% of patients have psychological problems, which lead to impotence. Usually patients who present with incomplete erection were involved in masturbation after puberty.

The objective of the clinical trial was to evaluate and establish the efficacy of Tentex Royal capsule in ED.

Material And Methods

An open clinical trial was conducted at Heritage Hospitals, Varanasi including 45 patients with a history of ED. Personal histories that included sexual and chronic diseases were recorded. A written, informed consent was obtained from all the patients. Each patient was given 2 capsules daily at night for 6 weeks. All the patients had follow-up to evaluate the effect of the drug and to rule out any side effects after the second week and then every week for a further 4 weeks. Those patients with no erection or who did not respond within 6 weeks had continued treatment for 12 weeks and more.

The initial evaluation was done with a detailed history and physical examination including preliminary assessment to determine if psychological factors were involved in the causation of ED. With respect to the laboratory investigations, a complete blood count, blood chemistry and testosterone assay tests were done. Since a majority of the patients were in the psychological group for ED, no other organic investigations were carried out.

Results

Out of 45 patients included in this study, 40 patients completed the treatment. 32 (80%) showed significant clinical improvement. They had erections good enough for intercourse.

Out of 40 patients who completed the study, 30 patients had psychological problem due to a history of masturbation, extra-marital affairs or post-marriage anxiety neurosis.

Patients with incomplete erection responded well to Tentex Royal capsules. Sixteen patients (40%) were cured in 3 weeks. Another 12 patients (30%) showed improvement in 6 weeks (Table 1). Seven patients who did not show any improvement during 6 weeks were requested to continue with the treatment for 12 weeks.

Table 1: Response to Tentex Royal capsule in incomplete erection
Duration of treatmentPatients curedPercent (%)
3 weeks1845
6 weeks1435
Total3280

Twelve patients who had no erection and loss of libido were evaluated at 12 weeks and later (Table 2).

Table 2: Response to Tentex Royal capsule in patients with no erection and loss of libido
Duration of treatmentPatients showing temporary improvement
12 weeks4
Above 12 weeks8
Total12

Serum testosterone level marginally increased in patients with incomplete erection after 6 weeks of treatment. Semen analysis also showed an increase in quantity and quality of sperm.

Discussion

Tentex Royal capsule contains an extract of Tribulus terrestris and powders of Asteracantha longifolia, Prunus amygdalus, Blepharis edulis and Crocus sativus.

The herbs mentioned above have been conventionally used in the management of ED for centuries. Tribulus terrestris has been clinically proven to improve sexual desire and enhance erection. The pharmacological properties of Tribulus terrestris extracts have been studied on the rabbit corpus cavernosum muscles. The extract showed increase in relaxation of cavernosum smooth muscles in a dose-dependent manner. Prunus amygdalus extract showed a significant increase in the sperm content and the motility in the epididymides and vas deferens. Prunus amygdalus has been used as an aphrodisiac in Arab Medicine. Crocus sativus, saffron is used in medicine as an aphrodisiac and antioxidant agent.

Clinical trials in progress at various academic institutions in India, have shown encouraging results in patients with ED without producing any side-effects. This indicates the safety of Tentex Royal capsule on repeated and long-term administration. Moreover, Phase I study showed that Tentex Royal capsule are well-tolerated without producing any abnormality on hematological, biochemical and physiological functions.

This open clinical trial has shown that Tentex Royal capsule is effective in patients with incomplete erection as well as in patients with no erection and loss of libido.

Conclusion

Considering the results of the clinical trial, it can be concluded that Tentex Royal capsule is effective and safe in patients with incomplete erection. A total of 80% patients responded to Tentex Royal capsule within the stipulated period of treatment.

References

  1. Feldman HA, Goldstein, I, Hatzichristou, DG, et al. (1994). Impotence and its medical and psychological correlates: Results of the Massachusetts male aging study. J. Urol., 151, 54-61.
  2. Gillenwater, JY. (1997). International impotence education month. AUA News, 2, 11.
  3. Overmyer, M. (1996). Impotence clinics find what medicine has overlooked. Urology Times, 24, 1.
  4. Adimoelja, A. (2000). Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfucntions. Int. J. Androl., 23(Suppl. 2), 82-84.
  5. Adaikan, PG, Gauthaman K, Prasad R.N and NG S.C. (2000). Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann. Acad. Med. Singapore, 29(1), 22-26.
  6. Qureshi S, Shah AH, Tariq M. and Ageel AM. (1989). Studies on herbal aphrodisiacs used in arab system of medicine. Am. J. Chin. Med., 17(1-2), 57.
  7. Kazuho Abe and Hiroshi Saito. (2000). Effects of Saffron extract and its constituent crocin on learning behavior and long-term potentiation. Phytotherapy Research, 14, 149-152.

Saturday, 29 October 2011

Le traitement efficace de l'impuissance - Cialis tadalafil

Cialis tadalafil est l'un des traitements les plus prescrits contre l'impuissance et le dysfonctionnement érectile. Le Tadalafil, ingrédient actif de online pharmacy appartient à la classe des médicaments appelés inhibiteurs de la phosphodièsterase de type 5. Les deux autres pilules contre l'impuissance approuvées par le FDA (Food and Drug Administration), le Viagra (Sildénafil) et Levitra (Vardenafil) appartiennent à la même classe de médicaments. Par conséquent, les trois pilules populaires du traitement de l’impuissance fonctionnent quasiment de la même façon. Cependant, beaucoup d'hommes préfèrent Cialis Tadalafil par rapport au Viagra et Levitra en raison de sa durée et rapidité d’action.

Comme le Viagra et le Levitra, le Cialis Tadalafil dilate les vaisseaux sanguins dans le pénis lors d’une stimulation sexuelle afin que plus de sang puisse se précipiter dans le pénis. Le pénis se remplit alors de sang et vous obtenez une érection ferme, prolongée et suffisante pour avoir un rapport sexuel satisfaisant. Cialis Tadalafil agit environ 30 minutes après sa prise et les effets se ressentent sur l'organisme pendant 36 heures. Concernant Viagra et Levitra, ils commencent à agir dans l'organisme environ une heure après la prise et leurs effets durent pendant 4 heures. Donc Cialis Tadalafil permet plus de spontanéité dans l'acte sexuel. Cialis Tadalafil, très populaire chez les hommes, est donc surnommé « La pilule de week-end » grâce à sa durée d’action.

Cialis Tadalafil a montré des résultats prometteurs dans les essais cliniques et a donc été approuvé par la FDA comme traitement contre l’impuissance. Cialis est un médicament sur ordonnance, sûr et efficace, disponible sur le marché depuis l’année 2003. Depuis plus de 6 ans, des millions d'hommes souffrant de l'impuissance ont bénéficié de ce médicament et ont amélioré leur vie sexuelle. Au fil des années, la popularité du Cialis Tadalafil continue à augmenter. Cela prouve l’efficacité de Cialis Tadalafil en tant que traitement contre l'impuissance.

Monday, 23 May 2011

Best of health care jokes

STOP: Skip this posting and read the one above it! This is like cotton candy compared to real nourishing food above.

Another high risk posting, this of health care-related jokes I have received over the years. This is problematic in that I have discovered that most medicine-related jokes are offensive or demeaning in some way. I do not repeat those -- or even admit whether I find them funny or not! -- and so you have to help me to decide if the remaining ones make the grade.

---

Hospital regulations require a wheelchair for patients being discharged. However, while working as a student nurse, I found one elderly gentleman -- already dressed and sitting on the bed with a suitcase at his feet -- who insisted he didn't need my help to leave the viagra.

After a chat about rules being rules, he reluctantly let me wheel him to the elevator. On the way down I asked him if his wife was meeting him.

"I don't know," he said. "She's still upstairs in the bathroom changing out of her cialis gown."

---

A mechanic was removing a cylinder-head from the motor of a Harley motorcycle when he spotted a well-known cardiologist in his shop. The cardiologist was there waiting for the service manager to come take a look at his bike when the mechanic shouted across the garage, "Hey Doc, want to take a look at this?"

The cardiologist, a bit surprised, walked over to where the mechanic was working on the motorcycle. The mechanic straightened up, wiped his hands on a rag and asked, "So Doc, look at this engine. I open its heart, take the valves out, repair any damage, and then put them back in, and when I finish, it works just like new. So how come I make $39,675 a year and you get the really big bucks ($1,695,759) when you and I are doing basically the same work?"

The cardiologist paused, smiled and leaned over, then whispered to the mechanic...''Try doing it with the engine running."

---

For those of you in a quandary when considering your health insurance options, I offer the following Q and A:

Q. What does HMO stand for?
A. This is actually a variation of the phrase, "HEY MOE." Its roots go back to a concept pioneered by Moe of the Three Stooges, who discovered that a patient could be made to forget the pain in his foot if he was poked hard enough in the eye.

Q. I just joined an HMO. How difficult will it be to choose the doctor I want?
A. Just slightly more difficult than choosing your parents. Your insurer will provide you with a book listing all the doctors in the plan. The doctors basically fall into two categories: those who are no longer accepting new patients, and those who will see you but are no longer participating in the plan. But don't worry, the remaining doctor who is still in the plan and accepting new patients has an office just a half-day's drive away.

Q. Do all diagnostic procedures require pre-certification?
A. No. Only those you need.

Q. Can I get coverage for my preexisting conditions?
A. Certainly, as long as they don't require any treatment.

Q. What happens if I want to try alternative forms of medicine?
A. You'll need to find alternative forms of payment.

Q. My pharmacy plan only covers generic drugs, but I need the name brand. I tried the generic medication, but it gave me a stomach ache. What should I do?
A. Poke yourself in the eye.

Q. What if I'm away from home and I get sick?
A. You really shouldn't do that.

Q. I think I need to see a specialist, but my doctor insists he can handle my problem. Can a general practitioner really perform a heart transplant right in his/her office?
A. Hard to say, but considering that all you're risking is the $20 co-payment, there's no harm in giving it a shot.

Q. Will health care be different in the next century?
A. No, but if you call right now, you might get an appointment by then.

---

The Board of BIDMC, feeling it was time for a shakeup, hired Paul Levy to be the new CEO. This new boss is determined to rid the institution of all slackers and bring real fiscal discipline.

On a tour of the facilities, Paul notices a guy leaning on a wall near the staff lounge. The room is full of doctors, nurses and aides and he wants to let them know he means business!

The CEO walks up to the guy and asks, "And how much money do you make a week?" A little surprised, the young fellow looks at him and replies, "I make $300.00 a week. Why?"

Paul, towering over the guy, then hands him $1,200 in cash and screams, "Here's four weeks pay, now GET OUT and don't come back!"

Feeling pretty good about his first firing, a slightly taller Paul looks around the room and asks, "Does anyone want to tell me what that goof-off did here?"

With a sheepish grin, one of the radiologists, mouth full of pepperoni, mutters, "He is the pizza delivery guy from Dominos...."

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True menu listing from our cafeteria:

Whole Wheat Pasta w/ Summer Vegetables Deglazed w/ Marsala Whine

Tuesday, 3 May 2011

What is Viagra ?

What is cheap cialis ?

Now if you are wondering, what's hell on the earth that made me write a blog entry about "viagra", please don't wonder, I will explain you in detail. Well, I have been receiving lots of Spam mails recently on my Gmail Id. Not sure how the spammers predicted that I need cialis, its such a wrong prediction but still they spammed me with hundred odd mails on lots of information on Viagra. Of course, Viagra happens to be a good scientific topic to do research on, so I thought of doing some research on Viagra. Things like, what is viagra, why do people feel shy when someone speaks about Viagra, I just wanted to know the exact reasons. Curiosity, my friends, it has always allowed me to understand lots of things. Let me say you, this post can really help you in gaining vital information about Viagra and probably in future if you find someone needing information on this, you can pass it on. Also, I will be describing all the terms very scientifically to reduce the embarrassment of all my blog readers. Common, I am not committing a crime by writing this blog, after all I am trying is to pass on real scientific information on Viagra, irrespective of whether you like or not. As a scientist I have the liberty of speaking truth over shyness.

Viagra is a chemical drug named 1-[4-ethoxy-3-(6,7-dihydro-1-methy l- 7 -oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl) phenylsulfonyl] -4-methylpiperazine citerate also called as "Sildenafil". Viagra just happens to be the commercial name of sildenafil sold by a company named “Pfizer”. Molecular formula of sildenafil is C22H30N6O4S. The basic function of Sildenafil is to increase the blood pressure in the vessels carrying blood to and fro the lungs. This generally causes shortness of breath, dizziness and tiredness. Now, one question in your mind must be what made Sildenafil so famous whereas it’s just a simple drug that increases blood pressure. The answer is very scientific and very much related to our lives, of course, if you have a deficiency.

The male organ of human Copulation has to be filled with vascular sinuses and should be capable of becoming distended and rigid as the result of being filled with blood during the course of copulation for a certain period of time. Some unfortunate men (!!) have a deficiency called as “erectile dysfunction” which reduces their ability to retain rigidity in the phallus during human copulation. Here comes Sildenafil as a rescue to such people to enjoy their lives. Sildenafil increases the blood flow to the human male phallus during human copulation. To be more scientific, Sildenafil improves pulmonary arterial hypertension by relaxing the blood vessels in the lungs to allow blood to flow easily. I guess, that’s the best way I can describe the Sildenafil without using so called “non-aesthetic terms”, in fact, I should add this paragraph on Wikipedia. Wow, I read the paragraph again, it has turned out great compared to the descriptions given across the other websites.

To clear out few things, Sildenafil doesn’t increase sexual urge, doesn’t cure erectile dysfunction and doesn’t prevent sexually transmitted diseases. It’s just a normal drug made extra famous by certain impotent people. Some of you might be thinking, how does sildenafil look like, is it a tablet, syrup or syringe? Sildenafil is sold in markets under the registered name “Viagra” as tablets. The tablets come as 25mg, 50mg and 100mg; consult a doctor before you take any of the different versions of tablets. There are few side-effects of Sildenafil but there cannot be anything worst than suffering from erectile dysfunction, so I suggest you to take it, cause you got a life, live it. But don’t take Sildenafil in large quantities (10 pills for an ever lasting night) as it can cause you a heart attack as well, anyhow that’s the worst case for the people over 40-50 years old. I really don’t think there is anyone who is above 30 reading my blog at present. By the way, according to Einstein’s relativity, an object experiences lesser time when it is riding fast but the actual time is more than what is observed, so don’t get dissatisfied by your life cause it was really quick, it may be due to relativity and unnecessary don’t take sildenafil.

What else should I write more about Viagra/Sildenafil? Damn, don’t ever think that I have consumed or seen it anytime. By the way, as per one of the Spam mails I received, “Viagra are blue tablets”, so now you know the color of viagra. So, let me conclude this blog article this way, don’t be shy in acquiring knowledge but yes, you got to have control over your senses. Life is a very valuable thing, don’t waste it reading non-sense available over net, science is the best source that you can trust upon. As a scientist, it is my responsibility to provide fellow human beings with right information as much as I can; this article is one such honest attempt.

November 04 4:11 AM

2007

My Consultant, Doctor Invisible

I started my surgical placement 3 weeks ago, and in that time, I have met my consultant precisely zero times. For the first two weeks, he was on leave, and for the last week, I have tried desperately but in vain to catch a fleeting glimpse of the lesser-spotted senior order cialis. Our lack of contact is not as worrying for me as it should be for you, seeing as he is the most important resource in the education of 3 people who will in the very near future be shoving their hands around in your guts and playing "eeny meeny miny mo" to decide which artery to clamp. I have parasitically sucked as much information out of the junior doctors as I can, and the occasional scheduled teaching session with another class is all well and good, but basically I'm on my own, and it isn't good.

At the risk of shattering the public's illusions of consultant surgeons as hardworking, humility-bound bundles of benevolent cuddliness, I have found a few incriminating photos taken during his time spent "at work". Observe.






Here he is shooting a personal best of 4-over-par when he was meant to be conducting an urgent radical nephrectomy.

Here he is in Monaco with his latest Porsche, whilst Mr.Smith bleeds out on the table thanks to his unsupervised cretinous underling doctors.



And here is cheap cialis Workshy again, coating himself in the gentle, relaxing sunbeams of Muscle Beach, as his own patients are ironically dying of untreated skin cancer.

Fine, maybe I'm overreacting, but it's not my fault if the weekly schedule of his activities I was given is 100% inaccurate. I'd ask the cleaners how to do a cystoscopy, but they only speak Polish. Just pray you don't need an operation in 10 years!